Treatment of infectious ulcers by fly Maggot
When modern medicine is incapable, the tendency towards ancient medicine is often created. The use of fly larvae for the elimination of necrotic tissue known as larval, magnetotherapy, or lumbar surgery dates back to the onset of human civilization. In contrast, the intolerance of patients with infectious ulcers to treatment, the laryngoscope acts around the world due to its high efficiency, safety and ease of use. Clinical reasons for the use of larval treatment, especially in infectious wounds, are those that are resistant to several drugs, and serious complications that make surgery impossible. Flies that are most commonly used in larvae are those belonging to the optional mycelium of the calibra family and the genus sericata Lucilia. This review summarizes the interesting and delusional history of larval treatment from the beginning to the present and includes the mechanisms of action and its clinical applications. It can also pave the way for future research.
In Islamic sources, worms appear in the body of the Prophet’s Aive, and after that, his wounds were healed. Historical sources also show the use of the Indian Indians and some Spanish tribes from worms to treat wounds.
The first reports about the use of larvae for the treatment of wounds to ancient times return. At that time, this method was widely used throughout the world. From the 16th century onwards, various physicians at the war fronts reported the effects of flying larvae on the treatment of ulcers in 1556, 1827, 1860 and 1920.
For the first time in 1556, the third specialist physician in France reported the importance of flying larvae in the treatment of diseases. In 1827, the head of the Napoleonic army medical team reported the importance of flying larvae in the treatment of ulcers. In the course of the American Civil War in 1860, two doctors who were involved in the treatment of war wounded reported this. In 1920, an officer of the US Army, who was sent to the French front during World War I to treat wounds to the French fronts, wounded two soldiers during the operation. In the wounds of these soldiers, they saw a large number of flying larvae and looked dismayed. There is no fever in their bodies; the wounds have not been infected and have been significantly accelerated in wound healing.
Today, physicians use miraculous effects of larvae to use a variety of flies to treat some types of ulcers. The first scientific studies on the use of Magotons by Dr. W. Boyer began.
During the 1920s and 1930s, Bayer reported successful treatment of bone infections and chronic ulcers in more than 90 patients using maggot. The discovery of penicillin and sulfa drugs in the 1940s caused a stop in magnetotherapy.
But now with the advent of antibiotic-resistant microbes, human medicine has returned to laryodynamics. The FDA approved this method in 2004. In addition to the United States, the new wave of the use of this method in that country has begun in countries such as England and Germany, so that by 2004, 70,000 people in the UK have been treated by this method.
Iranian physicians, as the 21st country, have started larval treatment at Baqiyatallah Hospital in Tehran. On December 16, 2004, in the orthopedics department of Baqiyatallah Al-Azam Hospital in Tehran, the first case of larval treatment of a 17-year-old young male foot, Mohammad Momeni, who was traumatized by a traumatic accident, had an amputation of the left knee joint, Done.
This young man was completely recovered after larating three times in 9 days. (The pictures below show the treatment steps)
Laroe Therapy in the New Age
Dead-wound wounds, spastic and ganglia wounds are good alternatives to laryopathy. In general, the use of larvae for an ulcer as the last method of defense is usually used after the patient has undergone antibiotic and surgical treatment for months and has not been successful.
One of the pioneers is the use of larval therapy in the new era of Dr. Sherman. He first experimented with the Therapy Maggot method, in which he ordered a large scar in his operating room, and then personally trapped the Lucilia sericata larvae, while observing the activity of the larvae and the effect Their amazing results in wound healing showed that larvae do not have the slightest effect on the human body.
He cites one of the amazing cases of larval treatment in which the intestine of a woman was perforated and the infection spread in the abdominal region damaged the intestinal wall. Doctors decided to try the use of larvae because surgery to remove the dead tissue of the intestine was very dangerous. The patient’s abdomen was opened and after placing two thousand larvae on the dead dress of dressing. Two days later the magnets were removed. No dead texture left. She recovered without the need for any other surgery.
Dr. John Dessari, about two samples treated at Baqiyatallah Hospital Tehran, said: “In 2 of our cases, one of them traveled under the train and was infected, so that he did not smell of infection, but he was close to him. Two or three days, when the larvae were laid on his wound, he completely recovered and completely cleansed after two or three treatments. So that we packed the skin and discharged him. Another case was a disease that had an infection after surgery. He could not even put his foot on the ground. After starting larval treatment, in addition to improving the infection, due to the loss of pain, we could monitor the weight very quickly and use the limb.
All baby babies (Magottes) are not suitable for larval treatment. Of the types that should not be used, members of the Sarcophagidae family and the hominovorax Cochliomyia species can be mentioned, as these species also swallow live tissue. The larvae most used for this work are related to the Calliphoridae family, and in particular Luciliasericata and Regina Phormia, which feed only dead tissues. The fly that puts this larva is not a home flies but lives in the desert. This flies detects and flies along the foxes and kilometers and sets it on the egg.
For successful larval treatment, magnots need to be free of any bacteria before they are placed on the wound. Recently, using a sterilization method, the fly eggs are diluted with sodium hypochlorite and then sterilized with water. They then put them in 4% formaldehyde and after washing with water they are placed in sterile containers for breeding, and the larvae, which are between 1-3 mm in length, are placed on an infected wound to destroy infectious tissues. .
In human medicine, a layer of hydrocolloids is prepared in the size and shape of the wound and placed on the wound. This protects the skin around the wound from the proteolytic enzyme of the larvae.
Instead, you can use zinc paste. On each centimeter of the wound, approximately 10 larvae are placed and the wound is dressed with a dressing. An absorbent pad is placed on top of the net to absorb liquid deposits and tissues. This pad can be changed if necessary. The larvae should be removed from the wound after 3 days. This is easily accomplished by removing the dressing and wounding with sterile salt solution.
If necessary, this can be repeated again. In general, the use of larvae can kill 10-15 g of dead cells per day. Larvae kill dead tissue by secreting gastric mucus and then swallowing tissues and soluble bacteria. Magogu lengths increase from about 2 mm to 10 mm during this period. The doctor has only a supervisory role in this process. Other antibiotic treatments can be used simultaneously with larval treatment.
Although the disease that uses this method does not require antibiotics, because the larva itself has an Allantoin antibiotic that infects the scar. Basically, wounds that do not respond to antibiotics, or because of the presence of rotten tissue and infection and antibiotics are not available to them, are good alternatives for magotrapa. Because there is a need for blood flow at the injury site to get an antibiotic, and the infection must first be surgically removed.
Therefore, virtually antibiotics can not do what the larvae do. Larvae act far beyond antibiotics. They also take antibiotics and also work the surgeon. Magnets are astounding. However, in many patients, it is unpleasant to imagine a larva on the wound.
Mechanism of larvae
The mechanism of action of larvae is as follows:
۱٫ In the salivary larvae, there is an Allantoin antibiotic that affects a wide range of bacteria;
۲٫ Larvae also produce ammonia which has a high microbial effect, as well as the pH of the wound to about 8.8 to 8.8. In this pH, colonization of the bacteria is difficult and wound healing is accelerated.
۳٫ In the head of the larvae there are sharp and abundant hair that the physical collision with the germs destroys a considerable part of them;
۴٫ Larvae also secrete Intolucin-6-like substances that accelerate wound healing and produce fibroblasts;
۵-Larvae also cause widespread hemorrhage with their widespread motions and wounds that give a mild massage;
۶٫ The X-ray does not have the smallest effect on the larvae, and the activity of the larvae decreases the moment from the moment of the wound, while by surgical procedure, due to the removal of the infectious and necrotic part, a part of the healthy tissue is removed by the surgeon.
Larvae kill dead tissues and activate healthy and healthy tissues. Cleansing the wounds from bacteria, while not harming healthy and healthy tissues. These worms eat nicotine and infectious tissue, and then they go out of the wound themselves. Laravirination is a well-known method for treating wounds and chronic infections that is practiced worldwide. In this method, the insect larvae are wound on the ulcer after they have emerged from the egg to feed the dead tissue of the wound. When the larvae reach puberty, they do not feed the wound, then replace it and place another larva on it.
General benefits of larval treatment
۱٫ In larval treatment, surgical removal of infectious tissue is not required.
۲٫ The treatment time is short (3 days in infective wounds and 4 months in diabetic infections)
۳٫ No need to be admitted to hospital.
۴٫ The cost of treatment is lower.
۵٫ During treatment, they only need oxygen.
Using Larumés for the treatment of diabetic wounds, bed sores, burns, carbuncle and certain types of benign and malignant tumors, dysplasia and fists, where other treatments do not respond or are not suitable for treatment, a very simple and relatively inexpensive method And in contrast to antibiotics, no complications have been reported.Learn therapy for breast cancer, burns, abscesses, SCC and semi-acute breast inflammation has been successful.If no response to medication and surgery, larvae The last method of wound healing is used.
Laravirin therapy is also useful when the patient’s health is at risk or unable to tolerate antibiotics. While oral and antibiotic antibiotics require extra blood supply to reach the affected area, maggots need only oxygen in an open sore to remove dead tissue and cleanse the wound from bacteria. Larvae also help eliminate all kinds of bacteria, including methicillin-resistant staphylococci. Using this method, treatment in diabetic patients lasts from one month to a maximum of 4 months, and in non-diabetic patients, it lasts from three days up to a maximum of 9 days. Studies in different cases show the amazing magnitude of the ability.
Most patients do not have any symptoms during treatment, but some may feel itchy, such as when they crawl something on the skin. When magnets grow up, due to stimulation of the nervous system, some patients may complain of pain, which can be remedied by removing larvae or using simple pills. On the second or third day, the wound will be plucked and watery. Except for these partial reactions, such a method does not leave any other negative reaction. This process usually does not last more than 72 hours.
Hope for the treatment of cancerous tumors
The larvae are necrotic tissue, that is, rotten, infected, and destroyed, pushed out and removed, but whether they can be used to treat tumors is a topic that needs research and There are more studies. In any case, the tumor should be surface so that larva can be placed on it. Should be researched on this subject.
The tumors, especially superficial tumors, may be treated with this method. Because the larvae eat nicotine tissue and the tumor produces nicotine tissue, it may be able to kill this tissue.
Beginning to use insects
Today, doctors use medical magotons to treat wounds by removing dead tissue and clearing them from lethal tissues. The use of magnots is part of a larger branch of medicine, called bio-therapy, in which organisms and living organisms, such as leeches or bees, are used as a direct therapeutic approach. Proponents of this therapeutic approach consider the future of biotechnology to be promising. They believe that biotechnology is going to be an inseparable branch of the treatment of injuries. Nature has been doing it for 300 million years. All that we do is use this blessing.
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